Intrinsic signal imaging data and list of reference papers
Mouse In Vivo Intrinsic Optical Signal Imaging (MiCAM ULTIMA-H)
- Sample
- Mouse In Vivo Bain (Somatosensory Barrel Cortex)
- Method
- Piezo Whisker Flick Stimulation
- Imaging System
- MiCAM ULTIMA
- Pixels
- 100x100 pixels
- Frame Rate
- 100fps (10msec/frame)
- Provided by
- Dr.Isabelle Ferezou and Dr.Carl C.H. Petersen, Brain Mind Institute, EPFL, Switzerland
Intrinsic Optical Signal (IOS) imaging
- Acute Ablation of Cortical Pericytes Leads to Rapid Neurovascular Uncoupling.
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Kassandra Kisler, Angeliki M. Nikolakopoulou, Melanie D. Sweeney, Divna Lazic, Zhen Zhao, and Berislav V. Zlokovic
Front Cell Neurosci. 2020; 14: 27.
- Temporal refinement of sensory-evoked activity across layers in developing mouse barrel cortex.
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Alexander van der Bourg, Jenq-Wei Yang, Maik C Stüttgen, Vicente Reyes-Puerta, Fritjof Helmchen, Heiko J Luhmann
Eur J Neurosci. 2019 Sep;50(6):2955-2969.
- In vivo imaging and analysis of cerebrovascular hemodynamic responses and tissue oxygenation in the mouse brain.
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Kassandra Kisler, Divna Lazic, Melanie D Sweeney, Shane Plunkett, Mirna El Khatib, Sergei A Vinogradov, David A Boas, Sava Sakadži & Berislav V Zlokovic
Nat Protoc. 2018 Jun;13(6):1377-1402.
- Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain.
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Kassandra Kisler, Amy R Nelson, Sanket V Rege, Anita Ramanathan, Yaoming Wang, Ashim Ahuja, Divna Lazic, Philbert S Tsai, Zhen Zhao, Yi Zhou, David A Boas, Sava Sakadžić & Berislav V Zlokovic
Nat Neurosci. 2017 Jan 30. doi: 10.1038/nn.4489.
- Probing the functional impact of sub-retinal prosthesis.
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Sébastien Roux, Frédéric Matonti, Florent Dupont, Louis Hoffart, Sylvain Takerkart, Serge Picaud, Pascale Pham, and Frédéric Chavane
eLife. 2016; 5: e12687. Published online 2016 Aug 23. doi: 10.7554/eLife.12687
- Susceptibility of Primary Sensory Cortex to Spreading Depolarizations.
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Volodymyr B. Bogdanov, Natalie A. Middleton, Jeremy J. Theriot, Patrick D. Parker, Osama M. Abdullah, Y. Sungtaek Ju, Jed A. Hartings, and K.C. Brennan
J Neurosci. 2016 Apr 27;36(17):4733-43. doi: 10.1523/JNEUROSCI.3694-15.2016.
- Orofacial Neuropathic Pain Leads to a Hyporesponsive Barrel Cortex with Enhanced Structural Synaptic Plasticity.
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Karine Thibault, Sébastien Rivière, Zsolt Lenkei, Isabelle Férézou, and Sophie Pezet
PLoS One. 2016 Aug 22;11(8):e0160786. doi: 10.1371/journal.pone.0160786. eCollection 2016.
- Sensory-Evoked Intrinsic Imaging Signals in the Olfactory Bulb Are Independent of Neurovascular Coupling.
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Roberto Vincis, Samuel Lagier, Dimitri Van De Ville, Ivan Rodriguez and Alan Carleton
Cell Rep. 2015 Jul 14;12(2):313-25. doi: 10.1016/j.celrep.2015.06.016. Epub 2015 Jul 2.
Flavoprotein Autofluorescence Imaging
- Numerical Analysis of Microcoil-Induced Electric Fields and Evaluation of In vivo Magnetic Stimulation of the Mouse Brain.
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Shunsuke Sugai, Hisaya Higuchi, Jun Nishikawa, Kazuo Satoh, Shuichi Murakami, Takashi Tateno
IEEJ Transactions on Electrical and Electronic Engineering, 15(11), 1672-1680.
- Potentiating a non-neuronal cardiac cholinergic system reinforces the functional integrity of the blood brain barrier associated with systemic anti-inflammatory responses.
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Shino Oikawa, Yuko Kai, Asuka Mano, Shuei Sugama, Naoko Mizoguchi, Masayuki Tsuda, Kazuyo Muramoto, Yoshihiko Kakinuma
Brain, Behavior, and Immunity 81 (2019) 122-137
- Sound- and current-driven laminar profiles and their application method mimicking acoustic responses in the mouse auditory cortex in vivo.
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Shuto Muramatsu, Masato Toda, Jun Nishikawa, Takashi Tateno
Brain Res. 2019 Oct 15;1721:146312.
- In vivo transcranial flavoprotein autofluorescence imaging of tonotopic map reorganization in the mouse auditory cortex with impaired auditory periphery.
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Kengo Takasu, Takashi Tateno
Hear Res. 2019 Jun;377:208-223.
- Micromagnetic Stimulation of the Mouse Auditory Cortex In Vivo Using an Implantable Solenoid System.
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Shunsuke Minusa, Hisayuki Osanai and Takashi Tateno
IEEE Trans Biomed Eng. 2018 Jun;65(6):1301-1310.
- Micro-coil-induced Inhomogeneous Electric Field Produces sound-driven-like Neural Responses in Microcircuits of the Mouse Auditory Cortex In Vivo.
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Hisayuk Osanai, Shunsuke Minusa and Takashi Tateno
Neuroscience. 2018 Feb 10;371:346-370.
- Flavoprotein fluorescence imaging-based electrode implantation for subfield-targeted chronic recording in the mouse auditory cortex.
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Jun Nishikawa, Yuto Ohtaka, Yuishi Tachibana, Yasutaka Yanagawa, Hisayuki Osanai, Takeaki Haga and Takashi Tateno
J Neurosci Methods. 2018 Jan 1;293:77-85.
- Salicylate-induced frequency-map reorganization in four subfields of the mouse auditory cortex.
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Yasutaka Yanagawa, Kengo Takasu, Hisayuki Osanai, Takashi Tateno
- Spatiotemporal dynamics of functional clusters of neurons in the mouse motor cortex during a voluntary movement.
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Riichiro Hira, Fuki Ohkubo, Katsuya Ozawa, Yoshikazu Isomura, Kazuo Kitamura, Masanobu Kano, Haruo Kasai and Masanori Matsuzaki
J Neurosci. 2013 Jan 23;33(4):1377-90. doi: 10.1523/JNEUROSCI.2550-12.2013.
Product suitable for this kind of application
- Fluorescence Mesoscope
- THT Series
The THT is a fluorescence widefield mesoscope developed for detecting low light fluorescence that is emitted from biological sample at a low magnicifation. This mesoscope has a very simple optical path combining two large-diameter objective lenses and a custom-made large fluorescent filter
- High Speed Imaging System
- MiCAM03-N256
MiCAM03-N256 is a high-speed imaging system that captures and visualizes small changes in fluorescence intensity from biological samples stained with fluorescent probes, such as voltage sensitive dyes and calcium dyes.
- Spatial Resolution :
-
128x128 - 256x256 pixles
(32x32 pixels - 256x256 pixles with option) - Maximum Frame Rate :
- 1,000fps
(20,000 fps available with option) - Up to 2 camera heads can be used with completely synchronization.